Serum Levels of Zinc and Magnesium in Newly Diagnosed Type-2 Diabetic Subjects.

Diabetes mellitus is a chronic metabolic disorder which affects carbohydrate, lipid and protein metabolism. There is a strong relation between some specific oligoelements and diabetes mellitus. The study was undertaken to determine serum levels of zinc and magnesium in 60 newly diagnosed uncomplicated type 2 diabetic (group I) and 60 healthy non-diabetic subjects (group II). Serum zinc and magnesium were estimated by Atomic Absorption Spectrophotometer (AAS). The serum zinc and magnesium levels were (72.70±8.43 μg/dl) and (1.85±0.17 mg/dl) respectively in group-1 and (75.92±8.20 μg/dl) and (2.00±0.17 mg/dl) respectively in group-11. The levels were significantly decreased in group-1. Study showed that type 2 diabetes mellitus can result in changes in zinc and magnesium levels and supplementation of both zinc and magnesium may be considered in those cases.

Dietary fibre and coronary heart disease.

Intake of dietary fibres lowers plasma lipids. Fibres particularly soluble ones lower serum total cholesterol (TC) and serum low-density lipoprotein cholesterol (LDL-C) without significant alteration in serum high-density lipoprotein cholesterol (HDL-C) and triacylglyccrol (TG). Consequently, the incidence of atherosclerotic heart diseases is lower in those who take high dietary fibre. Persons taking diet rich in saturated fat and poor in dietary fibre is more prone to develop coronary artery diseases. Dietary fibres also lower TC: HDL-C and LDL-C: HDL-C ratios. Higher TC: HDL-C and LDL-C: HDL-C ratios are in favour of development and progression of atherosclerotic vascular diseases, a pioneer cause of myocardial infarction (MI).

Turner syndrome: a case of gonadal dysgenesis.

An eighteen years old girl came from Ishargang, Mymensingh complaining of short stature, absence of development of breast, lack of menstruation and other secondary sex characters. She was found in infantile appearance with a height of 123 cm, body weight of 28 kg. She had short, broad, webbed neck, cuvitus valgus, absence of development of breast, axillary and public hairs with infantile external genitalia. Hormonal profile revealed high level of LH and FSH, low level of estrogens. Ultrasonography revealed uterine hypoplasia and ill defined gonadal streaks, Karyotype showed typical 45, X0 pattern. She was diagnosed as a case of gonadal dysgenesis due to Turner syndrome.